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kanal Katarakt tarla overall mutation load vs incidence of p53 mutations Tasarım harcama demode

Zinc shapes the folding landscape of p53 and establishes a pathway for  reactivating structurally diverse cancer mutants | eLife
Zinc shapes the folding landscape of p53 and establishes a pathway for reactivating structurally diverse cancer mutants | eLife

Mutant p53 drives the loss of heterozygosity by the upregulation of Nek2 in  breast cancer cells | Breast Cancer Research | Full Text
Mutant p53 drives the loss of heterozygosity by the upregulation of Nek2 in breast cancer cells | Breast Cancer Research | Full Text

Implications of driver genes associated with a high tumor mutation burden  identified using next‑generation sequencing on immunotherapy in  hepatocellular carcinoma
Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma

Clinical implications of subclonal TP53 mutations in acute myeloid leukemia  | Haematologica
Clinical implications of subclonal TP53 mutations in acute myeloid leukemia | Haematologica

TP53 oncomorphic mutations predict resistance to platinum‑ and taxane‑based  standard chemotherapy in patients diagnosed with advanced serous ovarian  carcinoma
TP53 oncomorphic mutations predict resistance to platinum‑ and taxane‑based standard chemotherapy in patients diagnosed with advanced serous ovarian carcinoma

Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with  the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes | HTML
Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes | HTML

Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral  and Cell-Based Immunotherapies
Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies

Systematic identification of mutations and copy number alterations  associated with cancer patient prognosis | eLife
Systematic identification of mutations and copy number alterations associated with cancer patient prognosis | eLife

Specific TP53 subtype as biomarker for immune checkpoint inhibitors in lung  adenocarcinoma - eBioMedicine
Specific TP53 subtype as biomarker for immune checkpoint inhibitors in lung adenocarcinoma - eBioMedicine

Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene

The impact of TP53 mutations and TP53 deletions on survival varies between  AML, ALL, MDS and CLL: an analysis of 3307 cases | Leukemia
The impact of TP53 mutations and TP53 deletions on survival varies between AML, ALL, MDS and CLL: an analysis of 3307 cases | Leukemia

TP53 alterations of hormone-naïve prostate cancer in the Chinese population  | Prostate Cancer and Prostatic Diseases
TP53 alterations of hormone-naïve prostate cancer in the Chinese population | Prostate Cancer and Prostatic Diseases

TP53 mutations as potential prognostic markers for specific cancers:  Analysis of data from The Cancer Genome Atlas and the International Agency  for Research on Cancer TP53 Database | bioRxiv
TP53 mutations as potential prognostic markers for specific cancers: Analysis of data from The Cancer Genome Atlas and the International Agency for Research on Cancer TP53 Database | bioRxiv

Targeting the Prion-like Aggregation of Mutant p53 to Combat Cancer |  Accounts of Chemical Research
Targeting the Prion-like Aggregation of Mutant p53 to Combat Cancer | Accounts of Chemical Research

Frontiers | Mutation-Derived Neoantigens for Cancer Immunotherapy
Frontiers | Mutation-Derived Neoantigens for Cancer Immunotherapy

Therapeutic targeting of mutant p53 in pediatric acute lymphoblastic  leukemia | Haematologica
Therapeutic targeting of mutant p53 in pediatric acute lymphoblastic leukemia | Haematologica

Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule  Stabilizers: the Y220X Paradigm | ACS Chemical Biology
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm | ACS Chemical Biology

LRP1B or TP53 mutations are associated with higher tumor mutational burden  and worse survival in hepatocellular carcinoma
LRP1B or TP53 mutations are associated with higher tumor mutational burden and worse survival in hepatocellular carcinoma

Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion -  ScienceDirect
Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion - ScienceDirect

Analysis of P53 mutations and their expression in 56 colorectal cancer cell  lines | PNAS
Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines | PNAS

TP53 mutational landscape of metastatic head and neck cancer reveals  patterns of mutation selection - ScienceDirect
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - ScienceDirect

Prevalence of germline TP53 mutation among early onset middle eastern  breast cancer patients | Hereditary Cancer in Clinical Practice | Full Text
Prevalence of germline TP53 mutation among early onset middle eastern breast cancer patients | Hereditary Cancer in Clinical Practice | Full Text

The TP53 mutation rate differs in breast cancers that arise in women with  high or low mammographic density | npj Breast Cancer
The TP53 mutation rate differs in breast cancers that arise in women with high or low mammographic density | npj Breast Cancer

High prevalence of TP53 loss and whole-genome doubling in early-onset  colorectal cancer | Experimental & Molecular Medicine
High prevalence of TP53 loss and whole-genome doubling in early-onset colorectal cancer | Experimental & Molecular Medicine

Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell  Lymphoma | NEJM
Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma | NEJM

TP53 mutational landscape of metastatic head and neck cancer reveals  patterns of mutation selection - eBioMedicine
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine